TABLE 4. STUDIES OF JOB STRAIN AND AMBULATORY BLOOD PRESSURE

First author Year Ref. Study participants Study Rating Effect of job strain
Cross-sectional studies
MEN
Theorell 1991 (109) 161 Swedish males aged 35-55 with borderline hypertension POSITIVE Significantly associated with work, home and sleep DBP** SBP (NS)
Harenstam 1988 (38) 66 male Swedish prison guards MIXED Skill use associated with work and leisure SBP**
Job demands and decision latitude (NS)
Sleep (n/a); DBP (n/a)
WOMEN
Theorell, 1993 (108) 56 female Swedish nurses and nurses aides POSITIVE Signif assoc with work SBP, DBP; SBP upon waking Leisure SBP, DBP; DBP upon waking [sleep] (NS)
MEN AND WOMEN
Van Egeren 1992 (116) 20 female and 17 male Michigan employees POSITIVE SBP:
Work= +12 mm Hg***;
Home= +7 mm Hg*;
Sleep=+7 mm Hg DBP:
Work= +4 mm Hg*;
Home, Sleep (NS)
Effect for both Males and Females
Light 1992 (75) Employed North Carolina men (n=65) and women (n=64), aged 18-47 MIXED MEN:
Work SBP= +6 mm Hg*;
Work DBP= +4 mm Hg*
WOMEN:
Work SBP= -1 mm Hg;
Work DBP= -2.2 mm Hg
(NS) Home or sleep BP (n/a
)
Case-control studies -- MEN
Schnall,

Landsbergis
1990
1992
1994
(100)

(101)
88 cases and 176 controls, males, aged 30-60, from New York City POSITIVE SBP:
Work=+6.8 mm Hg**;
Home=+6.5 mm Hg**;
Slp=+6.2 mm Hg**
DBP:
Work=+2.8 mm Hg*;
Home=+2.4 mm Hg* ;
Sleep=+1.7 mm Hg
Hypertension:
OR=2.7*; LVMI=9.7 g/m2 higher*
Cohort studies MEN AND WOMEN
Theorell, 1988 (114) 51 men, 22 women employed in 6 jobs in Stockholm followed for 1 year MIXED Work SBP higher (by 4 mm Hg) during highest vs. lowest job strain periods in 1 year*;
Work DBP (NS)
Effect for both Males and Females
Leisure SBP, DBP (NS);
Sleep (n/a)
MEN
Theorell, 1985 (113) 71 Stockholm men in 1981-82 followed for 10 yrs since age 18 MIXED NS; but significant interaction:
hypertensives have higher SBP rise at work if in a high strain job Sleep (n/a)
Schnall,
Schnall,
1992
1995
(99) 195 New York City men followed for 3 years POSITIVE For those in high strain jobs at both rounds (n=15) vs. those in non-strain jobs at both rounds (n=138):
Work SBP=5.6 mm Hg higher*;
Work DBP=4.0 mm Hg higher*
Home SBP=5.2 mm Hg higher*;
Home DBP=3.4 mm Hg higher*
Sleep SBP=4.9 mm Hg higher;
Sleep DBP=3.2 mm Hg higher.


BP, systolic blood pressure;
DBP, diastolic blood pressure;
BP, blood pressure
LVMI, left ventricular mass index;
SOR, standardized odds ratio;
OR, odds ratio;
NS, not significant at p<0.05.
*p<0.05; **p<0.01; ***p<.001.

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