JOB STRAIN AND AMBULATORY BLOOD PRESSURE 10-YEAR LONGITUDINAL FINDINGS FROM THE
WORK SITE BLOOD PRESSURE STUDY

Joseph Schwartz, PhD, SUNY - Stony Brook, Peter Schnall, MD, MPH, UC-Irvine, Paul Landsbergis, PhD, MPH, Thomas Pickering, MD, DPhil, Mt Sinai Medical Center


The Work Site Blood Pressure Study (WSBPS) in New York City recently completed its fourth wave (1996-2001) of data collection. It is the only long-term (up to 10 yrs) prospective study of job strain and blood pressure (BP) employing ambulatory BP (AmBP) monitoring. Analyses of these data allow us to estimate the effect of job strain, and changes in job strain, on AmBP.
The sample consists of employed individuals in New York City, 30-60 years of age: 308 were enrolled from 8 work sites between 1985-88 (Time 1), 34 from a 9th site plus 27 women from 2 of the original work sites between 1988-91 (Time 2), and 103 from a 10th work site at the end of Time 3 (1991-96), for a total of 472 participants (37% women, 33% non-Caucasian). Of the baseline sample, 94% were successfully followed, 77% completing a full re-evaluation.
Prior cross-sectional findings from the WSBPS provide some evidence for the effect of cumulative exposure. Relative to men without job strain at either Time 1 or Time 2, those with exposure at both times, i.e., "chronic exposure", had substantially higher systolic (11-12 mm Hg) and diastolic (6-9 mm Hg) AmBP at both Time 1 and Time 2, an effect that was greater than the cross-sectional effects at either Time (6-7 mm Hg systolic and 2-5 mm Hg diastolic). Prospective analyses, however, do not indicate a cumulative exposure effect as there was no change in AmBP over 3 years in the chronic exposure group (n=15).
There is also evidence that changes in job strain are associated with changes in AmBP. Men reporting job strain at Time 1 but not at Time 2 (n=25) exhibited a 3-year decrease in AmBP of 5.3/3.2 mm Hg at work and 4.7/3.3 mm Hg at home (p<.05). On the other hand, there was no significant change of BP in the group whose exposure changed from no job strain at Time 1 to job strain at Time 2.
At this conference we will present the first analyses using all four waves of data to re-evaluate 1) the cross-sectional effects of current job strain at each assessment, 2) the cross-sectional effects of cumulative job strain, and 3) the longitudinal association between changes in job strain and changes in AmBP. These results will provide a test of the generalizability of the prior findings from the first two waves of the study.

CORRESPONDING AUTHOR: Joseph E. Schwartz, Department of Psychiatry and Behavioral Science, 139 Putnam Hall, SUNY - Stony Brook, Stony Brook, NY 11794


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